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The recent US Presidential State Visit to the UK has catalysed a landmark £150 billion in new investment opportunities for UK businesses.

This is the largest commercial investment package ever secured during a State Visit. Marking a new phase of economic partnership between the two nations through supply chain integration and market expansion across key growth sectors.

Where the opportunities lie: key growth sectors and regional focus

The investment focuses on four high-growth sectors:

  • Clean energy;
  • Life sciences;
  • Advanced manufacturing; and 
  • Technology. 

The greatest opportunities lie in the high-growth sectors particularly in connection to the announcements from Blackstone whose £100 billion commitment over the next decade is likely to create substantial demand for UK service providers. Prologis's £3.9 billion investment in Cambridge and Daventry is also likely opening doors for life sciences and logistics companies seeking partnerships or expansion opportunities.

Importantly, the geographic spread of these investments means opportunities exist nationwide and not just restricted to the UK's major cities. Businesses in Belfast can tap into financial services expansion, while businesses across Glasgow, Warrington, the Midlands and North-East stand to benefit from growing manufacturing and technology partnerships. This initiative is projected to see 7600 high-quality jobs being created across the UK, within future-facing industries.

Government procurement unlocks business market opportunities

UK public sector spending with US companies is projected to increase substantially from £10 billion to £50 billion annually over a five-year period, £12 billion of which will specifically be allocated to technology and defence sectors. This expansion will create predictable demand patterns and partnership opportunities for UK businesses that are able to position themselves as suppliers or strategic partners to US companies fulfilling government contracts.

The bilateral nature of these investments also creates reciprocal opportunities which can allow UK enterprises to also scale and increase their presence across the US. Business and Trade Secretary Peter Kyle noted 'Working closely with the US strengthens our global position and delivers real results for British businesses'. This reflects established pathways being aligned for UK businesses to grow internationally while capitalising on inward investment opportunities at home.

Technology sector: primary beneficiary of investment opportunities

The technology sector emerges as the primary beneficiary of these investment opportunities, particularly driven by the rapid development of artificial intelligence and its applications across defence and energy sectors.

AI and data centre investments are creating immediate opportunities for UK technology companies. For example, Microsoft's £22 billion commitment to build the UK's largest supercomputer, alongside CoreWeave's £1.5 billion investment in AI data centres, is generating partnership opportunities for UK companies across the construction, energy, and technical services sectors. Pioneering advanced AI will be extremely valuable, allowing companies to position themselves for future innovation-led projects in both the public and private sectors. 

Technology investment is also creating high-value opportunities for qualified UK suppliers in the defence sector. Palantir's £1.5 billion investment is pushing demand for specialised UK companies capable of meeting security clearance requirements and providing defence-grade services.

With the increase of AI adoption, comes the need for a viable renewable energy source to meet increased demand. As a result, nuclear energy investments offer substantial long-term partnership opportunities. The X-Energy and Centrica programme, targeting 6GW of nuclear power capacity with potential economic value of £40 billion, present long term opportunities for UK engineering, construction, and specialist services companies.

Cross-border AI partnerships, such as the Nscale-OpenAI-NVIDIA collaboration establishing Stargate UK, demonstrate how UK companies can access global technology networks, gaining access to advanced AI tools and infrastructure systems while maintaining a strong domestic presence. These partnerships promote skill and knowledge sharing, supporting the upskill of company workforces whilst enhancing scalability and attracting further investment.

How UK businesses can respond

This investment package reflects the scale of shared ambitions shared by both nations. To capitalise on these opportunities, UK businesses should consider the following strategic actions:

  • Position for acquisition and partnership opportunities. Prologis's £3.9 billion investment in the Cambridge Biomedical Campus is expected to drive demand for specialist suppliers, research partners, and service providers.
  • Explore technology partnerships in emerging sectors. The quantum computing collaboration between OQC, NVIDIA and Digital Realty demonstrates how UK companies can access global markets through strategic alliances.
  • Consider expansion into new regions where US companies are establishing operations. Bank of America's first Northern Ireland operation creates opportunities for local service providers, while similar patterns emerge across other regions.

Develop capabilities in data services and AI support. Salesforce's £1.4 billion investment to make the UK an AI hub for Europe creates demand for UK companies offering data management, AI training, and technical support services.

Market access and regulatory advantages

The Tech Prosperity Deal and nuclear cooperation agreements signal streamlined regulatory pathways for UK-US business collaboration. This creates advantages for UK companies that can quickly establish US partnerships or expand operations.

Government backing for strategic sectors suggests faster approval processes and policy support for UK businesses entering these markets. However, companies should prepare for enhanced due diligence, particularly in defence and AI sectors where national security considerations apply.

To capitalise on these cross-border opportunities, UK businesses should prepare for increased cross-border opportunities by understanding export requirements, foreign investment procedures, and sector-specific regulations. The bilateral nature of these investments creates proven pathways for UK companies to access US markets while benefiting from US investment in the UK.

This historic investment package signals a new era of UK-US business integration that will require careful planning and expert guidance to realise its full potential. UK businesses that act early and align themselves with the regulatory pathways will increase chances of gaining competitive advantages in global markets.

Next steps for your business

This UK-US investment package creates a unique window of opportunity for UK businesses to scale, partner, and expand. Prime Minister Keir Starmer described it as ' a testament to Britain’s economic strength and a bold signal that our country is open, ambitious, and ready to lead'. Success will depend on moving quickly to identify relevant opportunities and positioning strategically within these high-growth sectors.

As a full-service international law firm, Trowers & Hamlins can help UK businesses navigate and capitalise on the opportunities arising from the UK-US investment package. Our Commercial team alongside colleagues across corporate, real estate, projects, employment, and regulatory practices can provide end-to-end support assisting from M&A's to joint ventures and partnerships.